Publications

Chen X, Gole J, Gore A, He Q, Lu M, Min J, Yuan Z, Yang X, Jiang Y, Zhang T, Suo C, Li X, Cheng L, Zhang Z, Niu H, Li Z, Xie Z, Shi H, Zhang X, Fan M, Wang X, Yang Y, Dang J, McConnell C, Zhang J, Wang J, Yu S, Ye W, Gao Y*, Zhang K*, Liu R*, Jin L*.

Non-invasive early detection of cancer four years before conventional diagnosis using a blood test.. Nat Commun. 2020 Jul 21;11(1):3475 *Co-corresponding Authors


Hartl C, Gao Y.

Proc Natl Acad Sci U S A. 2020 Jan 28;117(4):1849-1850. Clarifying the effect of library batch on extracellular RNA sequencing.

H.H. Jin, R. Snyder, A. Salbato, H. Manvelyan, H. Chen, H. Zheng, M. Li, L. Liu.

Preimplantation HLA genotyping with high-resolution next generation sequencing (NGS) in the same blastocyst biopsy collected for regular preimplantation genetic screen (PGS).


H.H. Jina, M. Lia, H. Zhenga, G.M. Davisa, H. Manvelyana, H. Chena, R. Snydera, A. Salbatoa, A. Kumarb, L. Liu

Use DNA fingerprinting to identify and confirm triploid embryos in whole genome next generation sequencing (NGS) preimplantation genetic screen (PGS).


Jaffe AE, Straub RE, Shin JH, Tao R, Gao Y, Collado-Torres L, Kam-Thong T, Xi HS, Quan J, Chen Q, Colantuoni C, Ulrich WS, Maher BJ, Deep-Soboslay A; (2018).

Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis. Nat Neurosci. 2018 Aug;21(8):1117-1125.


Tao R, Davis KN, Li C, Shin JH, Gao Y, Jaffe AE, Gondré-Lewis MC, Weinberger DR, Kleinman JE, Hyde TM. (2018).

GAD1 alternative transcripts and DNA methylation in human prefrontal cortex and hippocampus in brain development, schizophrenia. Mol Psychiatry. 2018 Jun;23(6):1496-1505.

L. W. Sundheimer, L. Liu, R. P. Buyalos, G. Hubert, Z. Al-Safi, M. Shamonki
Diagnosis of parental balanced reciprocal translocations by trophectoderm biopsy and comprehensive chromosomal screening
L. W. Sundheimer, R. P. Buyalos, G. Hubert, L. Liu, Z. Al-Safi, M. Shamonki
Identification of Previously Undetected Reciprocal Translocations by Comprehensive Chromosomal Screening of IVF Embryos in Patients with and without Recurrent Pregnancy Loss.
Shuang Hou, Jie-Fu Chen, Min Song, Yazhen Zhu, Yu Jen Jan, Szu Hao Chen, Tzu-Hua Weng, Dean-An Ling, Shang-Fu Chen, Tracy Ro, An-Jou Liang, Tom Lee, Helen Jin, Man Li, Lian Liu, Yu-Sheng Hsiao, Peilin Chen, Hsiao-Hua Yu, Ming-Song Tsai, Margareta D. Pisarska, Angela Chen, Li-Ching Chen, Hsian-Rong Tseng
Imprinted NanoVelcro Microchips for Isolation and Characterization of Circulating Fetal Trophoblasts: Toward Noninvasive Prenatal Diagnostics
T. Zore, L. Kroener, C. Wang, L. Liu, R.P. Buyalos, G. Hubert, M. Shamonki
Transfer of embryos with segmental mosaicism is associated with a significant reduction in live birth rate compared to euploid controls
A. Kaing,a L. Kroener,a R. Tassin,b M. Li,b L. Liu,c R. Buyalos,b G. Hubert,b M. Shamonki.a,b a Obstetrics and Gynecology, University of California Los Angeles, Los Angeles, CA; b Fertility and Surgical Associates of California, Thousand Oaks, CA; c PacGenomics, Agoura Hills, CA.
EARLIER DAY OF BLASTOCYST TROPHECTODERM BIOPSY IS PREDICTIVE OF EMBRYONIC EUPLOIDY ACROSS ALL AGE GROUPS IN BOTH AUTOLOGOUS AND DONOR CYCLES: ESSENTIAL DATA FOR COUNSELING PATIENTS.
M. Li, M. Shamonki, G. Hubert, R. Tassin, R. P. Buyalos. Fertility and Surgical Associates of California, Thousand Oaks, CA.
TESTICULAR SPERM CORRELATES WITH A SIMILAR RATE OF EUPLOID EMBRYO DEVELOPMENT COMPARED TO CYCLES USING EJACULATED SPERM.
M. Shamonki,a,b H. Jin,c Z. Haimowitz,d R. Buyalos,a L. Liu.c a Fertility and Surgical Associates of California, Thousand Oaks, CA; b UCLA Fertility and Reproductive Health Center, Los Angeles, CA; c PacGenomics, Agoura Hills, CA; d ART Reproductive Center, Beverly Hills, CA.
NON-INVASIVE PREIMPLANTATION GENETIC SCREENING (PGS) – FREE EMBRYONIC DNA IN EMBRYO CULTURE MEDIA EXISTS AND MAY OFFER THE POTENTIAL FOR COMPREHENSIVE CHROMOSOMAL SCREENING OF HUMAN BLASTOCYSTS.
Shamonki, M. I., Jin, H., Haimowitz, Z., & Liu, L. (2016)
Proof of concept: preimplantation genetic screening without embryo biopsy through analysis of cell-free DNA in spent embryo culture media. Fertility and Sterility, 106(6), 1312-1318.
Hwang T, Park CK, Leung AK, Gao Y, Hyde TM, Kleinman JE, Rajpurohit A, Tao R, Shin JH, Weinberger DR.(2016).
Dynamic regulation of RNA editing in human brain development and disease. Nat Neurosci. 2016 Aug;19(8):1093-9.
Jaffe AE, Gao Y, Deep-Soboslay A, Tao R, Hyde TM, Weinberger DR, Kleinman JE.(2015).
Mapping DNA methylation across development, genotype and schizophrenia in the human frontal cortex. Nat Neurosci. 2016 Jan;19(1):40-7.
Haiyan Zheng, Hua Jin, Lian Liu, Jianqiao Liu and Wei-Hua Wang (2015)

Application of next-generation sequencing for 24-chromosome aneuploidy screening of human preimplantation embryos. Zheng et al. Molecular Cytogenetics (2015) 8:38


Jin H.Snyder R., Zhou J., Li X., Davis G., Kishawi I.,  Liu L. (2013).

Validation of Short Turnaround Time Preimplantation Genetic Screen (PGS) Assay with Agilent CHG Array (PGS-Quick).


Jaffe AE, Shin J, Collado-Torres L, Leek JT, Tao R, Li C, Gao Y, Jia Y, Maher BJ, Hyde TM, Kleinman JE, Weinberger DR.(2015)

Developmental regulation of human cortex transcription and its clinical relevance at single base resolution. Nat Neurosci. 2015 Jan;18(1):154-61.


Auerbach SS, Phadke DP, Mav D, Holmgren S, Gao Y, Xie B, Shin JH, Shah RR, Merrick BA, Tice RR. (2015).

RNA-Seq-based toxicogenomic assessment of fresh frozen and formalin-fixed tissues yields similar mechanistic insights. J Appl Toxicol. 2015 Jul;35(7):766-80.

He, W., Sun, X., Liu, L., Li, M., Jin, H., & Wang, W.-H. (2014).

The prevalence of chromosomal deletions relating to developmental delay and/or intellectual disability in human euploid blastocysts. PloS One, 9(1), e85207.


Amarillo, I. E., Li, W. L., Li, X., Vilain, E., & Kantarci, S. (2014).

De novo single exon deletion of AUTS2 in a patient with speech and language disorder: a review of disrupted AUTS2 and further evidence for its role in neurodevelopmental disorders. American Journal of Medical Genetics. Part A, 164A(4), 958–965.


Arensman, M. D., Kovochich, A. N., Kulikauskas, R. M., Lay, A. R., Yang, P.-T., Li, X., … Dawson, D. W. (2014).

WNT7B mediates autocrine Wnt/ß-catenin signaling and anchorage-independent growth in pancreatic adenocarcinoma. Oncogene, 33(7), 899–908.


Braga, M., Reddy, S. T., Vergnes, L., Pervin, S., Grijalva, V., Stout, D., Li, X. … Singh, R. (2014).

Follistatin promotes adipocyte differentiation, browning, and energy metabolism. Journal of Lipid Research, 55(3), 375–384.


Gao, G., Vibranovski, M. D., Zhang, L., Li, Z., Liu, M., Zhang, Y. E., Li, X. … Wei, L. (2014).

A long-term demasculinization of X-linked intergenic noncoding RNAs in Drosophila melanogaster. Genome Research, 24(4), 629–638.


Mahmud, N., Petro, B., Baluchamy, S., Li, X., Taioli, S., Lavelle, D., … Araki, H. (2014).

Differential effects of epigenetic modifiers on the expansion and maintenance of human cord blood stem/progenitor cells. Biology of Blood and Marrow Transplantation: Journal of the American Society for Blood and Marrow Transplantation, 20(4), 480–489.


Sun, Y., Shi, N., Lu, H., Zhang, J., Ma, Y., Qiao, Y., Li, X. … Zhao, X. (2014).

ABCC4 copy number variation is associated with susceptibility to esophageal squamous cell carcinoma. Carcinogenesis.


Torres-Mora, J., Dry, S., Li, X., Binder, S., Amin, M., & Folpe, A. L. (2014).

Malignant melanotic schwannian tumor: a clinicopathologic, immunohistochemical, and gene expression profiling study of 40 cases, with a proposal for the reclassification of “melanotic schwannoma.” The American Journal of Surgical Pathology, 38(1), 94–105.


Wu, N. C., De La Cruz, J., Al-Mawsawi, L. Q., Olson, C. A., Qi, H., Luan, H. H., Li, X. … Sun, R. (2014).

HIV-1 quasispecies delineation by tag linkage deep sequencing. PloS One, 9(5), e97505.


Wu, N. C., Young, A. P., Al-Mawsawi, L. Q., Olson, C. A., Feng, J., Qi, H., Li, X. … Sun, R. (2014).

High-throughput identification of loss-of-function mutations for anti-interferon activity in influenza A virus NS segment. Journal of Virology.


Gao Y, Xie B, Liu R. (2014).

Delivering noninvasive prenatal testing in a clinical setting using semiconductor sequencing platform. Sci China Life Sci. 2014 Jul;57(7):737-8.

M. Li, H. Jin, R. Snyder, J. Zhou, L. Liu (2013).

Development and validation of a pacgenomics-agilent microarray system for preimplantation genetic screening (PGS) in patients undergoing in vitro fertilization (IVF). P-173 Tuesday, October 15, 2013.


Haddad G., He W., Gill J., Witz C., Wang C., Kaskar K., Wang W. (2013).

Mosaic pregnancy after transfer of a “euploid” blastocyst screened by DNA microarray. Journal of Ovarian Research 20136:70 DOI: 10.1186/1757-2215-6-70


Liang L., Wang C., Sun, X., Liu, L., Li, M., Witz, C., … Wang, W.-H. (2013).

Identification of chromosomal errors in human preimplantation embryos with oligonucleotide DNA microarray. PloS One, 8(4), e61838.


Farrell, J. J., Toste, P., Wu, N., Li, L., Wong, J., Malkhassian, D.,Li, X.… Donahue, T. R. (2013).

Endoscopically acquired pancreatic cyst fluid microRNA 21 and 221 are associated with invasive cancer. The American Journal of Gastroenterology, 108(8), 1352–1359.


Heneidi, S., Simerman, A. A., Keller, E., Singh, P., Li, X., Dumesic, D. A., & Chazenbalk, G. (2013).

Awakened by cellular stress: isolation and characterization of a novel population of pluripotent stem cells derived from human adipose tissue. PloS One, 8(6), e64752.


Kulkarni, R. P., Plaisier, S., Ra, S. H., Li, X., Lee, D. J., Hillman, J. D., & Binder, S. W. (2013).

Genetic profiling of BRAF inhibitor-induced keratoacanthomas reveals no induction of MAP kinase pathway expression. The Journal of Investigative Dermatology, 133(3), 830–833.


Lugassy, C., Wadehra, M., Li, X., Corsel Li, M., Akhavan, D., Binder, S. W., … Barnhill, R. L. (2013).

Pilot study on “pericytic mimicry” and potential embryonic/stem cell properties of angiotropic melanoma cells interacting with the abluminal vascular surface. Cancer Microenvironment: Official Journal of the International Cancer Microenvironment Society, 6(1), 19–29.


Magnusson, M., Sierra, M. I., Sasidharan, R., Prashad, S. L., Romero, M., Saarikoski, P., Li, X., … Mikkola, H. K. A. (2013).

Expansion on stromal cells preserves the undifferentiated state of human hematopoietic stem cells despite compromised reconstitution ability. PloS One, 8(1), e53912.


Nakatsu, M. N., Vartanyan, L., Vu, D. M., Ng, M. Y., Li, X., & Deng, S. X. (2013).

Preferential biological processes in the human limbus by differential gene profiling. PloS One, 8(4), e61833.


Nguyen Kovochich, A., Arensman, M., Lay, A. R., Rao, N. P., Donahue, T., Li, X., … Dawson, D. W. (2013).

HOXB7 promotes invasion and predicts survival in pancreatic adenocarcinoma. Cancer, 119(3), 529–539.


Ra, S. H., Su, A., Li, X., & Binder, S. (2013).

Molecularly enriched pathways and differentially expressed genes distinguishing cutaneous squamous cell carcinoma from pseudoepitheliomatous hyperplasia. Diagnostic Molecular Pathology: The American Journal of Surgical Pathology, Part B, 22(1), 41–47.


Su, A., Ra, S., Li, X., Zhou, J., & Binder, S. (2013).

Differentiating cutaneous squamous cell carcinoma and pseudoepitheliomatous hyperplasia by multiplex qRT-PCR. Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc, 26(11), 1433–1437.


Wu, L., Bluguermann, C., Kyupelyan, L., Latour, B., Gonzalez, S., Shah, S., Li, X., … Evseenko, D. (2013).

Human developmental chondrogenesis as a basis for engineering chondrocytes from pluripotent stem cells. Stem Cell Reports, 1(6), 575–589.


Zhang, J., Wu, T., Li, L., Han, S., Li, X., Zhang, S., & Qi, L. (2013).

Dynamic expression of small RNA populations in larch (Larix leptolepis). Planta, 237(1), 89–101.


Zhang, J., Zhang, S., Han, S., Li, X., Tong, Z., & Qi, L. (2013).

Deciphering small noncoding RNAs during the transition from dormant embryo to germinated embryo in Larches (Larix leptolepis). PloS One, 8(12), e814.


Zhang, J., Zhang, S., Li, S., Han, S., Wu, T., Li, X., & Qi, L. (2013).

A genome-wide survey of microRNA truncation and 3’ nucleotide addition events in larch (Larix leptolepis). Planta, 237(4), 1047–1056.


Yeo M, Berglund K, Hanna M, Guo JU, Kittur J, Torres MD, Abramowitz J, Busciglio J, Gao Y, Birnbaumer L, Liedtke (2013).

Bisphenol A delays the perinatal chloride shift in cortical neurons by epigenetic effects on the Kcc2 promoter. Proc Natl Acad Sci U S A. 2013 Feb 25.

Liu, J., Wang, W., Sun, X., Liu, L., Jin, H., Li, M., … Gill, J. (2012).

DNA microarray reveals that high proportions of human blastocysts from women of advanced maternal age are aneuploid and mosaic. Biology of Reproduction, 87(6), 148.


Chen, H., Sun, Y., Wu, C., Magyar, C. E., Li, X., Cheng, L., … Huang, J. (2012).

Pathogenesis of prostatic small cell carcinoma involves the inactivation of the P53 pathway. Endocrine-Related Cancer, 19(3), 321–331.


Donahue, T. R., Tran, L. M., Hill, R., Li, Y., Kovochich, A., Calvopina, J. H., Li, X., … Wu, H. (2012).

Integrative survival-based molecular profiling of human pancreatic cancer. Clinical Cancer Research: An Official Journal of the American Association for Cancer Research, 18(5), 1352–1363.


He, H., Xu, J., Warren, C. M., Duan, D., Li, X., Wu, L., & Iruela-Arispe, M. L. (2012).

Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages. Blood, 120(15), 3152–3162.


Johnstone, E. B., Davis, G., Zane, L. T., Cedars, M. I., & Huddleston, H. G. (2012).

Age-related differences in the reproductive and metabolic implications of polycystic ovarian syndrome: findings in an obese, United States population. Gynecological Endocrinology: The Official Journal of the International Society of Gynecological Endocrinology, 28(10), 819–822.


Koh, S. S., Wei, J.-P. J., Li, X., Huang, R. R., Doan, N. B., Scolyer, R. A., … Binder, S. W. (2012).

Differential gene expression profiling of primary cutaneous melanoma and sentinel lymph node metastases. Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc, 25(6), 828–837.


Li, X., Zhou, J., Nahas, S. A., Wan, H., Hu, H., & Gatti, R. A. (2012).

Common copy number variations in fifty radiosensitive cell lines. Genomics, 99(2), 96–100.


Reeves, M. E., Baldwin, M. L., Aragon, R., Baldwin, S., Chen, S.-T., Li, X., … Amaar, Y. G. (2012).

RASSF1C modulates the expression of a stem cell renewal gene, PIWIL1. BMC Research Notes, 5, 239.


Zhang, S., Han, S., Li, W., Zhou, J., Li, X., & Qi, L. (2012).

miRNA regulation in fast- and slow-growing hybrid Larix trees. Trees, 26(5), 1597–1604.


Spitzer, T., Johnstone, E., Huddleston, H., Cedars, M., Davis, G., & Fujimoto, V. (2012).

FMR1 Repeats and Ovarian Reserve: CGG Repeat Number does not Influence Antral Follicle Count. J Fertiliz In Vitro, (2), 105.


Van Handel, B., Montel-Hagen, A., Sasidharan, R., Nakano, H., Ferrari, R., Boogerd, C. J., Li, X., … Mikkola, H. K. A. (2012).

Scl represses cardiomyogenesis in prospective hemogenic endothelium and endocardium. Cell, 150(3), 590–605.


Zhang, J., Zhang, S., Han, S., Wu, T., Li, X., Li, W., & Qi, L. (2012).

Genome-wide identification of microRNAs in larch and stage-specific modulation of 11 conserved microRNAs and their targets during somatic embryogenesis. Planta, 236(2), 647–657.


Zhang, M., Mathur, A., Zhang, Y., Xi, S., Atay, S., Hong, J. A., Li, X., … Schrump, D. S. (2012).

Mithramycin represses basal and cigarette smoke-induced expression of ABCG2 and inhibits stem cell signaling in lung and esophageal cancer cells. Cancer Research, 72(16), 4178–4192.


Zhang, Y., Zhang, S., Han, S., Li, X., & Qi, L. (2012).

Transcriptome profiling and in silico analysis of somatic embryos in Japanese larch (Larix leptolepis). Plant Cell Reports, 31(9), 1637–1657.


Hannum G, Guinney J, Zhao L, Zhang L, Hughes G, Sadda S, Klotzle B, Bibikova M, Fan JB, Gao Y, Deconde R, Chen M, Rajapakse I, Friend S, Ideker T, Zhang K (2012).

Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates. Mol Cell, 2013 Jan 24;49(2):359-367.


Church GM, Gao Y, Kosuri S (2012).

Next-generation Digital Information Storage in DNA. Science, 337,1628-1628


Valente, A.X.C.N, Shin, J.H., Sarkar, A., Gao, Y. (2012)

Rare coding SNP in DZIP1 gene associated with late-onset sporadic Parkinson's disease. Sci Rep, 2012;2:256.

Chacko, S. A., Sul, J., Song, Y., Li, X., LeBlanc, J., You, Y., … Liu, S. (2011).

Magnesium supplementation, metabolic and inflammatory markers, and global genomic and proteomic profiling: a randomized, double-blind, controlled, crossover trial in overweight individuals. The American Journal of Clinical Nutrition, 93(2), 463–473.


Graham, R. P. D., Dry, S., Li, X., Binder, S., Bahrami, A., Raimondi, S. C., … Folpe, A. L. (2011).

Ossifying fibromyxoid tumor of soft parts: a clinicopathologic, proteomic, and genomic study. The American Journal of Surgical Pathology, 35(11), 1615–1625.


Lindgren, A. G., Natsuhara, K., Tian, E., Vincent, J. J., Li, X., Jiao, J., … Clark, A. T. (2011).

Loss of Pten causes tumor initiation following differentiation of murine pluripotent stem cells due to failed repression of Nanog. PloS One, 6(1), e16478.


Ra, S. H., Li, X., & Binder, S. (2011).

Molecular discrimination of cutaneous squamous cell carcinoma from actinic keratosis and normal skin. Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc, 24(7), 963–973.


Sheth, S., Li, X., Binder, S., & Dry, S. M. (2011).

Differential gene expression profiles of neurothekeomas and nerve sheath myxomas by microarray analysis. Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc, 24(3), 343–354.


Thapa, D. R., Li, X., Jamieson, B. D., & Martínez-Maza, O. (2011).

Overexpression of microRNAs from the miR-17-92 paralog clusters in AIDS-related non-Hodgkin’s lymphomas. PloS One, 6(6), e20781.


Guo, J., Ma, D., Mo, H., Ball, M.P., Jang, M.H., Bonaguidi, M.A., Balazer, J.A., Eaves, H.L., Xie, B., Ford, E., Zhang, K., Ming, G.L., Gao, Y.* & Song, H.* (2011).

Neuronal activity modifies DNA methylation landscape in the adult brain. Nature Neuroscience 14, 1345–1351 *Co-corresponding Authors

Alejandro Colaneri, Nickolas G., Staffa, Jr., Fargo, D.C., Gao, Y., Wang, T., Peddada, S.D., and Birnbaumer, L (2011).

Expanded methyl-sensitive cut counting reveals hypomethylation as an epigenetic state that highlights functional sequences of the genome. Proc Natl Acad Sci U S A, Jun 7;108(23):9715-20.

Evseenko, D., Zhu, Y., Schenke-Layland, K., Kuo, J., Latour, B., Ge, S., Li, X., … Crooks, G. M. (2010).

Mapping the first stages of mesoderm commitment during differentiation of human embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America, 107(31), 13742–13747.


Jiao, F., Chiu, H., Jiao, Y., de Rijk, W. G., Li, X., Eckstein, E. C., … Gu, W. (2010).

Quantitative trait loci for tibial bone strength in C57BL/6J and C3H/HeJ inbred strains of mice. Journal of Genetics, 89(1), 21–27.


Kong, J., Kim, G. H., Wei, M., Sun, T., Li, G., Liu, S. Q., Li, X., … Li, Y. C. (2010).

Therapeutic effects of vitamin D analogs on cardiac hypertrophy in spontaneously hypertensive rats. The American Journal of Pathology, 177(2), 622–631.


Reeves, M. E., Baldwin, S. W., Baldwin, M. L., Chen, S.-T., Moretz, J. M., Aragon, R. J., Li, X., … Amaar, Y. G. (2010).

Ras-association domain family 1C protein promotes breast cancer cell migration and attenuates apoptosis. BMC Cancer, 10, 562.


Zhang, S., Zhou, J., Han, S., Yang, W., Li, W., Wei, H., … Qi, L. (2010).

Four abiotic stress-induced miRNA families differentially regulated in the embryogenic and non-embryogenic callus tissues of Larix leptolepis. Biochemical and Biophysical Research Communications, 398(3), 355–360.


Gilchrist, D.A., Dos Santos, G., Fargo, D.C., Xie., Gao Y., Li, L., and Adelman, K. (2010).

Pausing of RNA polymerase II disrupts DNA-encoded nucleosome organization to facilitate precise gene regulation. Cell. Volume 143, Issue 4, 12 November 2010, pp 540-551.


Ni, T. Corcoran, D., Rach, E., Song, S., Spana, E., Gao, Y., Ohler, U., and Zhu, J. (2010)

A paired-end sequencing strategy to map the complex landscape of transcription initiation. Nature Methods. Vol. 7, No. 7. (23 May 2010), pp. 521-527


Wu, H., Sun, S., Tu, K., Gao, Y., Xie, B., Krainer, A.R., Zhu, J. (2010).

A splicing-independent function of SF2/ASF in microRNA processing. Molecular Cell. Volume 38, Issue 1, 67-77, 9 April 2010.


Nechaev, S., Fargo, D.C., Santos, G.D., Liu, L., Gao, Y. and Adelman K. (2010).

Global Analysis of Short RNAs Reveals Widespread Promoter-Proximal Stalling and Arrest of Pol II. Science. 2010 Jan 15;327(5963): 335-8. Epub 2009 Dec 10.High lighted in Science 327(5963):248, “To Stall or Not to Stall”.

Jiao, Y., Cai, C., Kermany, M. H., Yan, J., Cai, Q., Miller, D., Li, X., … Gu, W. (2009).

ENU induced single mutation locus on chr 16 leads to high-frequency hearing loss in mice. Genes & Genetic Systems, 84(3), 219–224.


Jiao, Y., Jin, X., Yan, J., Jiao, F., Li, X., Roe, B. A., … Gu, W. (2009).

An insertion of intracisternal A-particle retrotransposon in a novel member of the phosphoglycerate mutase family in the lew allele of mutant mice. Genes & Genetic Systems, 84(5), 327–334.


Sharff, K. A., Song, W.-X., Luo, X., Tang, N., Luo, J., Chen, J., Li, X., … He, T.-C. (2009).

Hey1 Basic Helix-Loop-Helix Protein Plays an Important Role in Mediating BMP9-induced Osteogenic Differentiation of Mesenchymal Progenitor Cells. The Journal of Biological Chemistry, 284(1), 649–659.


Cho, B-K, Zengler, K., Qiu, Y., Park, Y.S., Knight, E., Barrett, C., Gao, Y. Palsson, B.O. (2009).

Elucidation of the Transcription Unit Architecture of the Escherichia coli K-12 MG1655 Genome. Nature biotechnology. Vol. 27, No. 11. (01 November 2009), pp. 1043-1049. Cover Story


Zhang* K, Li* JB, Gao* Y, Egli D, Xie B, Lee JH, Aach J, LeProust E, Eggan K, Church GM (2009).

Digital RNA Allelotyping Reveals Tissue-specific and Allele-specific Gene Expression in Human. Nature Methods. Aug;6(8):613-8.*Equal Contribution


Li*, J., Levanon*, E.Y., Yoon, J.K., Aach, J., Xie, B., LeProust, E., Zhang, K., Gao, Y., Church, G.M. (2009)

Genome-wide Identification of Human RNA Editing Sites by Massively Parallel DNA Capturing and Sequencing Technologies. Science. 324(5931):1210-3. * Equal Contribution


Li* JB, Gao* Y, Aach* J, Zhang* K, Kryukov* GV, Xie B, Ahlford A, Yoon J-K, Rosenbaum AM, Zaranek AW, LeProust E, Sunyaev SR, Church GM (2009).

Multiplex padlock targeted sequencing reveals human hypermutable CpG variations. Genome Research. 2009 Sep;19(9):1606-15. * Equal Contribution


Deng, J., Shoemaker, R., Xie, B., Gore, A., Leproust, E., Antosiewica-Bourget, J., Egli, D., Maherali, N., Park, I-H, Yu, J., Daley, G.Q., Eggan, K., Hochedlinger, K., Thomson, J., Wang, W., Gao*, Y., Zhang*, K. (2009)

Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming. Nature Biotechnology. 27:353-60. * Co-corresponding Authors, Article, Cover Story [Commentaries by: (1) Berman BP, Weisenberger DJ, Laird PW (2009) Locking in on the human methylome. Nature Biotechnology 27: 341-342. (2) Rusk N (2009) Capturing the human methylome. Nature Methods 6:320-321. (3) Swanson J (2009) A global view of methylation. Genome Technology June 2009 Issue, 92:29-31]


Ball*, M.P., Li*, J.B., Gao, Y., Lee, J., LeProust, E. Park, I.H. Xie, B. Daley, G.Q. Church, G.M. (2009)

Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells. Nature Biotechnology. 2009 Apr;27(4)361-8. * Equal Contribution, Article, Cover Story [Commentaries by: (1) Berman BP, Weisenberger DJ, Laird PW (2009) Locking in on the human methylome. Nature Biotechnology 27: 341-342. (2) Rusk N (2009) Capturing the human methylome. Nature Methods 6:320-321. (3) Swanson J (2009) A global view of methylation. Genome Technology June 2009 Issue, 92:29-31]


Valente*#, A.X.C.N., Robert*, S.B., Buck, G.A. and Gao#, Y. (2009).

Functional Organization of the Yeast Proteome by a Novel Yeast Interactome Map. Proc Natl Acad Sci U S A. 2009 Feb 3;106(5);1490-5* Equal Contribution; # Co-corresponding Authors

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Eaves, H.L. and Gao, Y. (2009)

MOM: Maximum Oligonucleotide Mapping. Bioinformatics. 25:969-70.

DeUgarte, C. M., Li, M., Surrey, M., Danzer, H., Hill, D., & DeCherney, A. H. (2008).

Accuracy of FISH analysis in predicting chromosomal status in patients undergoing preimplantation genetic diagnosis. Fertility and Sterility, 90(4), 1049–1054.


Jiao, Y., Jin, X., Yan, J., Zhang, C., Jiao, F., Li, X., … Gu, W. (2008).

A deletion mutation in Slc12a6 is associated with neuromuscular disease in gaxp mice. Genomics, 91(5), 407–414.


Li, X., Quigg, R. J., Zhou, J., Gu, W., Nagesh Rao, P., & Reed, E. F. (2008).

Clinical utility of microarrays: current status, existing challenges and future outlook. Current Genomics, 9(7), 466–474.


Schrump, D. S., Fischette, M. R., Nguyen, D. M., Zhao, M., Li, X., Kunst, T. F., … Steinberg, S. M. (2008).

Clinical and molecular responses in lung cancer patients receiving Romidepsin. Clinical Cancer Research: An Official Journal of the American Association for Cancer Research, 14(1), 188–198.


Shahine, L. K., Kuppermann, M., Davis, G., Creasman, J., & Cedars, M. I. (2008).

Patient willingness to participate in a clinical trial with preimplantation genetic diagnosis. Fertility and Sterility, 89(4), 879–884.


Wang, Q., Li, Y. C., Wang, J., Kong, J., Qi, Y., Quigg, R. J., & Li, X. (2008).

miR-17-92 cluster accelerates adipocyte differentiation by negatively regulating tumor-suppressor Rb2/p130. Proceedings of the National Academy of Sciences of the United States of America, 105(8), 2889–2894.


Wang, Q., Wang, Y., Minto, A. W., Wang, J., Shi, Q., Li, X., & Quigg, R. J. (2008).

MicroRNA-377 is up-regulated and can lead to increased fibronectin production in diabetic nephropathy. FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology, 22(12), 4126–4135.


Chiu, R., Chan, A., Gao, Y., Lau, V., Zheng, W., Leung, T., Foo, C., Xie, B., Tsui, N., Lun, F., Zee, B., Lau., T., Cantor, C., Lo, Y.M. (2008).

Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma. Proc Natl Acad Sci U S A. Vol. 105, No. 51. (23 December 2008), pp. 20458-20463 2008 Top 10 Medical Breakthrough by Times Magazine.

Bao, L., Wang, Y., Chang, A., Minto, A. W., Zhou, J., Kang, H., … Quigg, R. J. (2007).

Unrestricted C3 activation occurs in Crry-deficient kidneys and rapidly leads to chronic renal failure. Journal of the American Society of Nephrology: JASN, 18(3), 811–822.


Dobson, A. T., Davis, R. M., Rosen, M. P., Shen, S., Rinaudo, P. F., Chan, J., & Cedars, M. I. (2007).

Methylenetetrahydrofolate reductase C677T and A1298C variants do not affect ongoing pregnancy rates following IVF. Human Reproduction (Oxford, England), 22(2), 450–456.


Jiao, Y., Yan, J., Jiao, F., Yang, H., Donahue, L. R., Li, X., … Gu, W. (2007).

A single nucleotide mutation in Nppc is associated with a long bone abnormality in lbab mice. BMC Genetics, 8, 16.


Li, X., Wang, H., Touma, E., Qi, Y., Rousseau, E., Quigg, R. J., & Ryaby, J. T. (2007).

TP508 accelerates fracture repair by promoting cell growth over cell death. Biochemical and Biophysical Research Communications, 364(1), 187–193.


Li, X., Wang, H., Touma, E., Rousseau, E., Quigg, R. J., & Ryaby, J. T. (2007).

Genetic network and pathway analysis of differentially expressed proteins during critical cellular events in fracture repair. Journal of Cellular Biochemistry, 100(2), 527–543.


Thurman, J. M., Lenderink, A. M., Royer, P. A., Coleman, K. E., Zhou, J., Lambris, J. D., … Holers, V. M. (2007).

C3a is required for the production of CXC chemokines by tubular epithelial cells after renal ishemia/reperfusion. Journal of Immunology (Baltimore, Md.: 1950), 178(3), 1819–1828.


Yan, J., Jiao, Y., Jiao, F., Stuart, J., Donahue, L. R., Beamer, W. G., Li, X., … Gu, W. (2007).

Effects of carbonic anhydrase VIII deficiency on cerebellar gene expression profiles in the wdl mouse. Neuroscience Letters, 413(3), 196–201.


Yan, J., Jiao, Y., Li, X., Jiao, F., Beamer, W. G., Rosen, C. J., & Gu, W. (2007).

Evaluation of gene expression profiling in a mouse model of L-gulonolactone oxidase gene deficiency. Genetics and Molecular Biology, 30(2), 322–329.


Zhang, Z., Yuan, W., Sun, L., Szeto, F. L., Wong, K. E., Li, X., … Li, Y. C. (2007).

1,25-Dihydroxyvitamin D3 targeting of NF-kappaB suppresses high glucose-induced MCP-1 expression in mesangial cells. Kidney International, 72(2), 193–201.


Porreca GJ, Zhang K, Li JB, Xie B, Austin D, Vassallo SL, Leproust EM, Peck BJ, Emig CJ, Dahl F, Gao Y, Church GM, and Shendure J (2007).

Multiplex Amplification of Large Sets of Human Exons. Nature Methods. 4(11):931-936.

Bianco, K., Caughey, A. B., Shaffer, B. L., Davis, R., & Norton, M. E. (2006).

History of miscarriage and increased incidence of fetal aneuploidy in subsequent pregnancy. Obstetrics and Gynecology, 107(5), 1098–1102.


Fishel, M. L., Rabik, C. A., Bleibel, W. K., Li, X., Moschel, R. C., & Dolan, M. E. (2006).

Role of GADD34 in modulation of cisplatin cytotoxicity. Biochemical Pharmacology, 71(3), 239–247.


He, Q., Wan, C., Li, X., Lee, G., Gardiner, T., & Li, G. (2006).

PERIPHERAL BLOOD DERIVED MESENCHYNAL STEM CELLS IN THE GFP RATS. Journal of Bone & Joint Surgery, British Volume, 88-B(SUPP III), 405–405.


Li, M. (2006).

Dual Differential Stain Protocol: Blastocyst Cell Discrimination and Number Determination. The Clinical Embryologist, 9(2), 34–35.


Li, X., Quigg, R. J., Zhou, J., Xu, S., Masinde, G., Mohan, S., & Baylink, D. J. (2006).

A critical evaluation of the effect of population size and phenotypic measurement on QTL detection and localization using a large F2 murine mapping population. Genetics and Molecular Biology, 29(1), 166–173.


Qi, L., Li, X., Zhang, S., & An, D. (2006).

Genetic regulation by non-coding RNAs. Science in China. Series C, Life Sciences / Chinese Academy of Sciences, 49(3), 201–217.


Schrump, D. S., Fischette, M. R., Nguyen, D. M., Zhao, M., Li, X., Kunst, T. F., … Steinberg, S. M. (2006).

Phase I study of decitabine-mediated gene expression in patients with cancers involving the lungs, esophagus, or pleura. Clinical Cancer Research: An Official Journal of the American Association for Cancer Research, 12(19), 5777–5785.


Si, W., Kang, Q., Luu, H. H., Park, J. K., Luo, Q., Song, W.-X., Li, X., … He, T.-C. (2006).

CCN1/Cyr61 is regulated by the canonical Wnt signal and plays an important role in Wnt3A-induced osteoblast differentiation of mesenchymal stem cells. Molecular and Cellular Biology, 26(8), 2955–2964.


Wang, Y., Zhou, J., Minto, A. W., Hack, B. K., Alexander, J. J., Haas, M., … Quigg, R. J. (2006).

Altered vitamin D metabolism in type II diabetic mouse glomeruli may provide protection from diabetic nephropathy. Kidney International, 70(5), 882–891.


Zhou, M., Li, X., & Lavker, R. M. (2006).

Transcriptional profiling of enriched populations of stem cells versus transient amplifying cells. A comparison of limbal and corneal epithelial basal cells. The Journal of Biological Chemistry, 281(28), 19600–19609.

Chang, A., Zhou, J., Minto, A. W., & Quigg, R. J. (2005).

Is Laser Capture Microdissection (LCM) A Viable Approach To Determine Transcriptional Changes In Glomeruli? Presented at the ASN.


Chiu, T., Li, M., Marin De Ugarte, C., & Hill, D. (2005).

Surrogate Live Birth of a Normal Baby for a Patient with Marfan Syndrome. Presented at the Pacific Coast Reproductive Society.


Hill, D., Buehler, N., Jiang, Z., Surrey, M., Danzer, H., & Li, M. (2005).

In Vitro Fertilization – Embryo Transfer Combined with Aneuploidy Screening of Day Three Embryos Lowers the Miscarriage Rate in Recurrent Pregnancy Loss Patients of Advanced Maternal Age. Presented at the Pacific Coast Reproductive Society.


Hill, D., Li, M., Marin De Ugarte, C., Danzer, H., Surrey, M., & DeCherney, A. (2005).

Day 3 morphology as a predictor of aneuploidy. Presented at the American Society for Reproductive Medicine; Pacific Coast Reproductive Society.


Hill, D., Li, M., Marin De Ugarte, C., Sarajari, S., Buehler, N., Surrey, M., … DeCherney, A. (2005).

The relationship between cleavage rate and morphology to aneuploidy in day three human embryos. Presented at the American Society for Reproductive Medicine.


Jiao, Y., Li, X., Beamer, W. G., Yan, J., Tong, Y., Goldowitz, D., … Gu, W. (2005).

A deletion causing spontaneous fracture identified from a candidate region of mouse Chromosome 14. Mammalian Genome: Official Journal of the International Mammalian Genome Society, 16(1), 20–31.


Jiao, Y., Yan, J., Zhao, Y., Donahue, L. R., Beamer, W. G., Li, X., … Gu, W. (2005).

Carbonic anhydrase-related protein VIII deficiency is associated with a distinctive lifelong gait disorder in waddles mice. Genetics, 171(3), 1239–1246.


Li, M., Marin De Ugarte, C. M., Surrey, M., Danzer, H., DeCherney, A., & Hill, D. L. (2005).

Fluorescence in situ hybridization reanalysis of day-6 human blastocysts diagnosed with aneuploidy on day 3. Fertility and Sterility, 84(5), 1395–1400.


Li, M., Marin De Ugarte, C., Danzer, H., Surrey, M., DeCherney, A., & Hill, D. (2005).

Rescue ICSI and PGD: the combination can result in pregnancy. Presented at the American Society for Reproductive Medicine; Pacific Coast Reproductive Society.


Li, M., Marin De Ugarte, C., Danzer, H., Surrey, M., & Hill, D. (2005).

Determination of Mosaicism in Early Human Embryos by Confirmation FISH. Presented at the Pacific Coast Reproductive Society.


Li, X., & Quigg, R. J. (2005).

An integrated strategy for the optimization of microarray data interpretation. Gene Expression, 12(4-6), 223–230.


Li, X., Quigg, R. J., Zhou, J., Ryaby, J. T., & Wang, H. (2005).

Early signals for fracture healing. Journal of Cellular Biochemistry, 95(1), 189–205.


Marin De Ugarte, C., Ambartsumyan, G., Li, M., Hill, D., & DeCherney, A. (2005).

Successful selection of normal embryos using PGD in a woman with Spinocerebellar Ataxia Type 3. Presented at the Pacific Coast Reproductive Society.


Masinde, G., Li, X., Baylink, D. J., Nguyen, B., & Mohan, S. (2005).

Isolation of wound healing/regeneration genes using restrictive fragment differential display-PCR in MRL/MPJ and C57BL/6 mice. Biochemical and Biophysical Research Communications, 330(1), 117–122.


Minto, A. W., Zhou, J., Chang, A., & Quigg, R. J. (2005).

Novel Genes in Progressive Mesangioproliferative Glomerulonephritis (MesPGN). Presented at the ASN.


Sarajari, S., Marin De Ugarte, C., Li, M., DeCherney, A., & Hill, D. (2005).

Aneuploidy in Day 3 embryos where in pronuclei(PN) were not observed following routine insemination or Intracytoplasmic sperm injection ICSI). Presented at the American Society for Reproductive Medicine.


Thurman, J. M., Royer, P. A., Zhou, J., Quigg, R. J., & Holers, V. M. (2005).

Renal Ischemia/Reperfusion Induces the Production of Multiple Chemotactic Factors Due to Alternative Pathway Complement Activation. Presented at the ASN.


Wang, H., Li, X., Tomin, E., Doty, S. B., Lane, J. M., Carney, D. H., & Ryaby, J. T. (2005).

Thrombin peptide (TP508) promotes fracture repair by up-regulating inflammatory mediators, early growth factors, and increasing angiogenesis. Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society, 23(3), 671–679.


Wang, H., Zhang, Y.-M., Li, X., Masinde, G. L., Mohan, S., Baylink, D. J., & Xu, S. (2005).

Bayesian shrinkage estimation of quantitative trait loci parameters. Genetics, 170(1), 465–480.


Xiang, W., Kong, J., Chen, S., Cao, L.-P., Qiao, G., Zheng, W., Li, X., … Li, Y. C. (2005).

Cardiac hypertrophy in vitamin D receptor knockout mice: role of the systemic and cardiac renin-angiotensin systems. American Journal of Physiology. Endocrinology and Metabolism, 288(1), E125–132.


Xie, J.-T., Mehendale, S. R., Li, X., Quigg, R., Wang, X., Wang, C.-Z., … Yuan, C.-S. (2005).

Anti-diabetic effect of ginsenoside Re in ob/ob mice. Biochimica Et Biophysica Acta, 1740(3), 319–325.


Xinmin, L., Kim, J., Zhou, J., Gu, W., & Quigg, R. (2005).

Use of signal thresholds to determine significant changes in microarray data analyses. Genetics and Molecular Biology, 28(2), 191–200.


Zheng, W., & Zhou, J. (2005).

Current English Chinese Laboratory Molecular Biology Protocols. Beijing: Concord Medical University Press.


Gao, Y., and Church, G. (2005).

Improving Molecular Cancer Classification through Sparse Non-Negative Matrix Factorization. Bioinformatics. 21: 3970-3975.

Hill, D. L., & Li, M. (2004).

What regulations for preimplantation genetic diagnosis? Journal of Assisted Reproduction and Genetics, 21(1), 11–13.


Li, M., & Hill, D. (2004a).

Embryo biopsy medium may hold the key to successful outcomes following pre-implantation genetic diagnosis. Presented at the European Society of Human Reproduction and Embryology.


Li, M., & Hill, D. (2004b).

FISH reanalysis on day 6 human blastocysts diagnosed with aneuploidy on day 3: does day 3 single cell biopsy accurately represent the numerical chromosomal status of the embryo? Presented at the European Society of Human Reproduction and Embryology.


Li, M., & Hill, D. (2004c).

Pregnancies by PGD for translocation carriers using single interphase cell FISH with chromosome-specific breakpoint spanning probes. Presented at the Pacific Coast Reproductive Society.


Li, M., Kumar, A., Marin De Ugarte, C., Surrey, M., Danzer, H., DeCherney, A., & Hill, D. (2004).

Does “Embryo Glue®” help embryos in their implantation? Presented at the American Society for Reproductive Medicine.


Li, M., Marin De Ugarte, C., Danzer, H., Surrey, M., DeCherney, A., & Hill, D. (2004).

Comparison of Computer Assisted Infrared Laser with acid Tyrone solution in zone drilling for embryo biopsy. Presented at the American Society for Reproductive Medicine.


Li, M., Marin De Ugarte, C., Jiang, Z., Danzer, H., Surrey, M., & Hill, D. (2004).

Towards a single blastocyst transfer: PGD in combination with morphology selection could be the ultimate tool. Presented at the American Society for Reproductive Medicine.


Luo, Q., Kang, Q., Si, W., Jiang, W., Park, J. K., Peng, Y., Li, X., … He, T.-C. (2004).

Connective tissue growth factor (CTGF) is regulated by Wnt and bone morphogenetic proteins signaling in osteoblast differentiation of mesenchymal stem cells. The Journal of Biological Chemistry, 279(53), 55958–55968.


Marin De Ugarte, C., Li, M., DeCherney, A., Danzer, H., Surrey, M., & Hill, D. (2004).

Accuracy of FISH in predicting chromosomal status in PGD patients. Presented at the American Society for Reproductive Medicine.


Marin De Ugarte, C., Li, M., DeCherney, A., Surrey, M., Danzer, H., & Hill, D. (2004).

Do patients who undergo Preimplantation Genetic Diagnosis have higher pregnancy rates and should fewer embryos be transferred? Presented at the American Society for Reproductive Medicine.


Peng, Y., Kang, Q., Luo, Q., Jiang, W., Si, W., Liu, B. A., Li, X., … He, T.-C. (2004).

Inhibitor of DNA binding/differentiation helix-loop-helix proteins mediate bone morphogenetic protein-induced osteoblast differentiation of mesenchymal stem cells. The Journal of Biological Chemistry, 279(31), 32941–32949.


Renville, J., Marin De Ugarte, C., Li, M., Hill, D., Surrey, M., & DeCherney, A. (2004).

Are families with 3 children of the same sex more likely to have the next child of the same sex? Presented at the American Society for Reproductive Medicine.

Bao, L., Zhou, J., Holers, V. M., & Quigg, R. J. (2003).

Excessive matrix accumulation in the kidneys of MRL/lpr lupus mice is dependent on complement activation. Journal of the American Society of Nephrology: JASN, 14(10), 2516–2525.


Gu, W.-, Li, X.-, Roe, B., Lau, K.-, Edderkaoui, B., Mohan, S., & Baylink, D. (2003).

Application of Genomic Resources and Gene Expression Profiles to Identify Genes That Regulate Bone Density. Current Genomics, 4(1), 75–102.


Li, X., Zheng, W., & Li, Y. C. (2003).

Altered gene expression profile in the kidney of vitamin D receptor knockout mice. Journal of Cellular Biochemistry, 89(4), 709–719.


Masinde, G. L., Wergedal, J., Davidson, H., Mohan, S., Li, R., Li, X., & Baylink, D. J. (2003).

Quantitative trait loci for periosteal circumference (PC): identification of single loci and epistatic effects in F2 MRL/SJL mice. Bone, 32(5), 554–560.


Mohan, S., Masinde, G., Li, X., & Baylink, D. J. (2003).

Mapping quantitative trait loci that influence serum insulin-like growth factor binding protein-5 levels in F2 mice (MRL/MpJ X SJL/J). Endocrinology, 144(8), 3491–3496.


Peng, Y., Kang, Q., Cheng, H., Li, X., Sun, M. H., Jiang, W., … He, T.-C. (2003).

Transcriptional characterization of bone morphogenetic proteins (BMPs)-mediated osteogenic signaling. Journal of Cellular Biochemistry, 90(6), 1149–1165.

Dyanov, H., Li, X., Petkova, M. M., Zhou, J., & Quigg, R. (2002).

Optimization of protocols for Affymetrix GeneChip array hybridization/nalysis system for increased detection sensitivity. Presented at the The 3rd Annual Northwest Microarray Conference, Seattle, Washington.


Gu, W. K., Li, X. M., Edderkaoui, B., Strong, D. D., Lau, K. H. W., Beamer, W. G., … Baylink, D. J. (2002).

Construction of a BAC contig for a 3 cM biologically significant region of mouse chromosome 1. Genetica, 114(1), 1–9.


Gu, W., Li, X., Lau, K.-H. W., Edderkaoui, B., Donahae, L. R., Rosen, C. J., … Baylink, D. J. (2002).

Gene expression between a congenic strain that contains a quantitative trait locus of high bone density from CAST/EiJ and its wild-type strain C57BL/6J. Functional & Integrative Genomics, 1(6), 375–386.


Li, M., Drury, K., Kipersztok, S., Rhoton-Vlasak, A., & Williams, R. (2002).

Efficiency of 12-chromosome aneuploidy diagnosis (2,7,8,13,14,15,16,18,21,22,Y and Y) by three round FISH test. Fertility and Sterility, 78(Suppl1), S183.


Li, X., Gu, W., Masinde, G., Covarrubias, M., Mohan, S., & Baylink, D. (2002).

Temporal analysis of gene expression by microarray during wound healing. Wounds, 67–78.


Li, X., Gu, W., Mohan, S., & Baylink, D. J. (2002).

DNA microarrays: their use and misuse. Microcirculation (New York, N.Y.: 1994), 9(1), 13–22.


Li, X., Masinde, G., Gu, W., Wergedal, J., Mohan, S., & Baylink, D. J. (2002).

Genetic dissection of femur breaking strength in a large population (MRL/MpJ x SJL/J) of F2 Mice: single QTL effects, epistasis, and pleiotropy. Genomics, 79(5), 734–740.


Li, X., Srivastava, A. K., Gu, W., Masinde, G., Mohan, S., & Baylink, D. J. (2002).

Opposing changes in osteocalcin levels in bone vs serum during the acquisition of peak bone density in C3H/HeJ and C57BL/6J mice. Calcified Tissue International, 71(5), 416–420.


Masinde, G. L., Li, X., Gu, W., Davidson, H., Hamilton-Ulland, M., Wergedal, J., … Baylink, D. J. (2002).

Quantitative trait loci (QTL) for lean body mass and body length in MRL/MPJ and SJL/J F(2) mice. Functional & Integrative Genomics, 2(3), 98–104.


Masinde, G. L., Li, X., Gu, W., Hamilton-Ulland, M., Mohan, S., & Baylink, D. J. (2002).

Quantitative trait loci that harbor genes regulating muscle size in (MRL/MPJ x SJL/J) F(2) mice. Functional & Integrative Genomics, 2(3), 120–125.


Masinde, G. L., Li, X., Gu, W., Wergedal, J., Mohan, S., & Baylink, D. J. (2002).

Quantitative trait loci for bone density in mice: the genes determining total skeletal density and femur density show little overlap in F2 mice. Calcified Tissue International, 71(5), 421–428.


Li, X., G. M. (2002).

Chromosomal regions harboring genes for the work to femur failure in mice. Functional & Integrative Genomics, 1(6), 367–74.


Xu, Y., Zhuang, G., Shu, Y., Li, M., Zhou, C., & Zhang, M. (2002).

Preimplantation gender diagnosis by fluorescence in situ hybridization. Chinese Medical Journal, 115(6), 874–877.

Kipersztok, S., Li, M., Drury, K., Williams, R., & Rhoton-Vlasak, A. (2001).

Use of Intracytoplasmic Sperm Injection (ICSI) in In-Vitro Fertilization (IVF) Cycles with Failed or Poor Fertilization. Reproductive Technologies, 10(6), 311–313.


Li, M., Drury, K., & Williams, R. (2001).

Suitability of Mouse Embryos for Human IVF QC: Zygotes vs. 2-cell Embryos. Fertility and Sterility, 76(3S1), S230.


Li, X., Gu, W., Masinde, G., Hamilton-Ulland, M., Rundle, C. H., Mohan, S., & Baylink, D. J. (2001a).

Genetic variation in bone-regenerative capacity among inbred strains of mice. Bone, 29(2), 134–140.


Li, X., Gu, W., Masinde, G., Hamilton-Ulland, M., Xu, S., Mohan, S., & Baylink, D. J. (2001b).

Genetic control of the rate of wound healing in mice. Heredity, 86(Pt 6), 668–674.


Li, X., Mohan, S., Gu, W., & Baylink, D. J. (2001).

Analysis of gene expression in the wound repair/regeneration process. Mammalian Genome: Official Journal of the International Mammalian Genome Society, 12(1), 52–59.


Li, X., Mohan, S., Gu, W., Wergedal, J., & Baylink, D. J. (2001).

Quantitative assessment of forearm muscle size, forelimb grip strength, forearm bone mineral density, and forearm bone size in determining humerus breaking strength in 10 inbred strains of mice. Calcified Tissue International, 68(6), 365–369.


Masinde, G. L., Li, X., Gu, W., Davidson, H., Mohan, S., & Baylink, D. J. (2001).

Identification of wound healing/regeneration quantitative trait loci (QTL) at multiple time points that explain seventy percent of variance in (MRL/MpJ and SJL/J) mice F2 population. Genome Research, 11(12), 2027–2033.


Srivastava, A. K., Bhattacharyya, S., Li, X., Mohan, S., & Baylink, D. J. (2001).

Circadian and longitudinal variation of serum C-telopeptide, osteocalcin, and skeletal alkaline phosphatase in C3H/HeJ mice. Bone, 29(4), 361–367.

Li, M., & Zhuang, G. (2000a).

Pregnancy after intracytoplasmic sperm injection using immotile, stump ejaculated and testicular spermatozoa. Journal of Reproductive Medicine (Chinese), 9(3), 178–179.


Li, M., & Zhuang, G. (2000b).

Using ejaculated,epididymal or testicular spermatoza to provide fertility for infertile men. Journal of Chinese Surgery, 38(4), 280–282.


Li, M., & Zhuang, G. (2000c).

Using testicular sperm to provide fertility for azoospermia men. National Medical Journal of China, 80(8), 588–590.


Srivastava, A. K., Bhattacharyya, S., Li, X., Mohan, S., & Baylink, D. J. (2000).

Circadian and longitudinal variation of serum C-telopeptide, osteocalcin, and skeletal alkaline phosphatase in C3H/HeJ mice. Bone, 29(4), 361–367.


Li, X., Mohan, S., Gu, W., Miyakoshi, N., & Baylink, D. J. (2000).

Differential protein profile in the ear-punched tissue of regeneration and non-regeneration strains of mice: a novel approach to explore the candidate genes for soft-tissue regeneration. Biochimica Et Biophysica Acta, 1524(2-3), 102–109.

Li, M., & Zhuang, G. (1999a).

Development potential of human embryos after blastomere biopsy. Journal of Reproductive Medicine (Chinese), 8(2), 107–109.


Li, M., & Zhuang, G. (1999b).

Frozen-thawed epididymal sperm intracytoplasmic sperm injection to treat infertility caused by obstructive azoospermia. Journal of Chinese Urology, 350(20), 6.


Gao, Y., Garzon, M., Murphy, R., Rose, J., Deaton, R., Franceschetti, and Stevens. E. (1999).

DNA Implementation of Nondeterminism. DIMACS Series in Discrete Mathematics and Theoretical Computer Sciences, vol. 48. 137-148.


Gao, Y., Mathee, K., Narasimhan, G., Wang, X. (1999).

Detection of HTH Motifs via Data Mining. Proceedings of SPIRE’ 99 – String Processing and Information Retrieval, 63-72.

Li, M., & Zhuang, G. (1998).

Cryopreservation noctoral emission and intracytoplasmic sperm injection to provide fertility for anejaculation men. Journal of Reproductive Medicine (Chinese), 7(1), 52–53.


Li, X., Li, M., & Zhuang, G. (1998).

Sex determination of pre-implantation embryos by nest PCR. Academic Journal of Sun Yat-Sen University of Medical Sciences, 19(1), 11–13.

Li, M., & Zhuang, G. (1997).

The relationship of serum P level on the day of hCG injection and pregnancy in in-vitro fertilization and embryo transfer. Chinese Journal of Practical Gynecology and Obstetrics, 13(3), 147–148.


Li, X., Guo, R., Pedersen, C., Hayman, D., & Langridge, P. (1997).

Physical localization of rRNA genes by two-colour fluorescent in-situ hybridization and sequence analysis of the 5S rRNA gene in Phalaris coerulescens. Hereditas, 126(3), 289–294.


Li, X., Paech, N., Nield, J., Hayman, D., & Langridge, P. (1997).

Self-incompatibility in the grasses: evolutionary relationship of the S gene from Phalaris coerulescens to homologous sequences in other grasses. Plant Molecular Biology, 34(2), 223–232.

Li, X., Nield, J., Hayman, D., & Langridge, P. (1996).

A self-fertile mutant of Phalaris produces an S protein with reduced thioredoxin activity. The Plant Journal: For Cell and Molecular Biology, 10(3), 505–513.

Li, X., Nield, J., Hayman, D., & Langridge, P. (1995).

Thioredoxin activity in the C terminus of Phalaris S protein. The Plant Journal: For Cell and Molecular Biology, 8(1), 133–138.

Li, X., Nield, J., Hayman, D., & Langridge, P. (1994).
Cloning a putative self-incompatibility gene from the pollen of the grass Phalaris coerulescens. The Plant Cell, 6(12), 1923–1932.
Li, X. M. (1992).
Synergistic effect of Adh alleles in Drosophila melanogaster. Proceedings. Biological Sciences / The Royal Society, 247(1318), 9–16.